Sustainability of Grants

 Centre for pluripotent cells and genome instability research (www)

Ministry of Education, Youth, and Sports, 2012-2014, No.CZ.1.07/2.3.00/20.0011
Principal investigator: Lumír Krejčí

The project is interdisciplinary extension, stabilization of research capacity and the introduction of new management system, evaluation and ethical principles into an existing platform of biology of human pluripotent stemcells (hPSC) at the Institute of Biology, Faculty of Medicine, Masaryk University in Brno. Activities of the centre will focus on the study of biology of hPSC in the area of identifying obstacles of their use for treatment of serious diseases – such as genome instability or the emergence of genetic abnormalities. Instability of the genome of hPSC will be studied from the perspective of culture conditions, the regulation of their self-renewal / differentiation using synthetic molecules and molecular mechanisms of DNA damage and repair.

Mendel lectures in 2012-2014 supported by Pluricell: here

Project: Centre for pluripotent cells and genome instability research – PLURICELL - CZ.1.07/2.3.00/20.0011 

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