Supported GAČR Projects:
Mgr. Lenka Bešše, PhD – ECPAS-mediated proteasome remodeling as a mechanism of resistance to proteasome inhibition in multiple myeloma
MUDr. Martin Pešl, PhD – Melatonin in human cardiomyocytes: cellular functions in normal cells and in a heart failure model
Dr. Nicola Silva – Identification of novel factors promoting and suppressing BRCA2 activity during meiotic DNA repair in Caenorhabditis elegans
prof. MUDr. David Šmajs, PhD – Identification of virulence factors of Treponema pallidum subsp. pallidum: from human transcriptomic data to in vitro strain characterization
Supported AZV ČR Projects:
Mgr. Andrej Bešše, Dr. sc. nat. – Identification of surface proteins modulating cytotoxic T-cell response in multiple myeloma using CRISPR activation screening
Mgr. Lenka Bešše, PhD – Study of proteasome inhibition combined with tyrosine kinase inhibition as a therapeutic option in triple-negative breast cancer
MUDr. Kateřina Slabá, PhD – Beyond the exome: Integration of precision genomics and functional validation in undiagnosed pediatric patients with negative whole-exome sequencing results
prof. MUDr. David Šmajs, PhD – Antibiotic resistance in Treponema pallidum subsp. pallidum: mapping emerging resistance in contemporary strains causing syphilis
