Emerging antibiotic resistance in Treponema pallidum subsp. pallidum: mapping of antibiotic resistance among contemporary syphilis strains (NW26-05-00404)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2026 — 12/2029
Investor: Ministry of Health of the CR / Ministry of Health Research Programme 2024 - 2030

Identification of virulence factors of Treponema pallidum subspecies pallidum: from human transcriptomic data to in vitro characterization of strains with inactivated genes (GA26-22086S)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2026 — 12/2028
Investor: Czech Science Foundation / Standard Projects

Bile acid malabsorption in oncology patients. Concept 3P Medicine (prevention of bile acid malabsorption associated complications, prediction, and personalization) (NW25-09-00063)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 5/2025 — 12/2028
Investor: Ministry of Health of the CR / Ministry of Health Research Programme 2024 - 2030

In vitro cultivation of Treponema pallidum: a new tool to study genetics and pathogen-host interaction of the agent of syphilis (GA23-07021S)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2023 — 12/2025
Investor: Czech Science Foundation / Standard Projects

National Institute of Virology and Bacteriology (LX22NPO5103)
MU Researcher: prof. RNDr. Robert Vácha, PhD.
MU Faculty or unit: Central European Institute of Technology
Project Period: 6/2022 — 12/2025
Investor: Ministry of Education, Youth and Sports of the CR / national recovery plan

A global syphilis vaccine targeting outer membrane proteins of Treponema pallidum (U19 AI144177)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 5/2019 — 4/2025
Investor: Ostatní - foreign / National Institutes of Health

Biomedical Sciences III (MUNI/A/1393/2022)
MU Researcher: prof. RNDr. Ondřej Slabý, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2023 — 12/2023
Investor: Masaryk University / Specific research - support for student projects

Genomic epidemiology of Treponema pallidum strains infecting women and men in low-income countries to inform syphilis vaccine development (INV-036560) (21-0119)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 11/2021 — 10/2023
Investor: Ostatní - foreign / Other foreign funds

Biomedical Sciences II (MUNI/A/1418/2021)
MU Researcher: prof. RNDr. Ondřej Slabý, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2022 — 12/2022
Investor: Masaryk University / Specific research - support for student projects

Treponematosis in representatives of the order Leporidae: genetic diversity of treponemal organisms and relationship with the human pathogen T. pallidum (GC18-23521J)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2018 — 1/2022
Investor: Czech Science Foundation / International projects

Genome-wide integrative analysis of DNA methylation and transcriptional expression of different lineages of Treponema pallidum subsp. pallidum, the causative agents of syphilis (MUNI/11/SUP/04/2020)
MU Researcher: Mgr. Linda Grillová, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 10/2020 — 1/2021
Investor: Masaryk University / Internal projects of the Faculty of Medicine

Cellular and Molecular Biology for Biomedical Sciences (MUNI/A/0951/2019)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2020 — 12/2020
Investor: Masaryk University / Grant Agency of Masaryk University

Development of a new typing system for the causative agent of syphilis, Treponema pallidum subsp. pallidum, focused on proteomic differences (17-31333A)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 4/2017 — 12/2020
Investor: Ministry of Health of the CR / Ministry of Health Research Programme 2015 - 2022

Molecular and Cellular Biology for Biomedical Sciences (MUNI/A/1087/2018)
MU Researcher: prof. Ing. Petr Dvořák, CSc.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2019 — 12/2019
Investor: Masaryk University / Grant Agency of Masaryk University

Study of pathogenic treponemal genomes based on single cell analysis (GA17-25455S)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2017 — 12/2019
Investor: Czech Science Foundation / Standard Projects

Cellular and Molecular Biology (MUNI/A/0754/2017)
MU Researcher: prof. Ing. Petr Dvořák, CSc.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2018 — 12/2018
Investor: Masaryk University / Grant Agency of Masaryk University

Increasing the interactivity and effectiveness of teaching practical exercises in Biology (MUNI/FR/0967/2017)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2018 — 12/2018
Investor: Masaryk University / MU Development Fund

Analysis of gastrointestinal microbiome in patients with primary immune deficiencies (MUNI/M/1322/2015)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 3/2016 — 12/2018
Investor: Masaryk University / Grant Agency of Masaryk University

Molecular characterization of novel bacteriocins identified in the genera Escherichia and Shigella (GA16-21649S)
MU Researcher: prof. MUDr. David Šmajs, Ph.D.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2016 — 12/2018
Investor: Czech Science Foundation / Standard Projects

Molecular and Cellular Biology (MUNI/A/0810/2016)
MU Researcher: prof. Ing. Petr Dvořák, CSc.
MU Faculty or unit: Faculty of Medicine
Project Period: 1/2017 — 12/2017
Investor: Masaryk University / Grant Agency of Masaryk University

All remaining research projects back to 1992.