2021

• Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function

  ŠPÍREK Mário TAYLOR M. R. G. BELÁŇ Ondrej BOULTON S. J. KREJČÍ Lumír

  Article in Periodical

  Nature Communications, year: 2021, volume: 12, edition: 1, DOI

• Single-molecule visualization of human RECQ5 interactions with single-stranded DNA recombination intermediates

  XUE C. Y. MOLNÁROVÁ Lucia STEINFELD J. B. ZHAO W. X. MA C. J. ŠPÍREK Mário KANIECKI K. KWON Y. BELAN Ondrej KREJČÍ Kateřina BOULTON S. J. SUNG P. GREENE E. C. KREJČÍ Lumír

  Article in Periodical

  Nucleic acids research, year: 2021, volume: 49, edition: 1, DOI

2020

• Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability

  BOOTH James Alexander ŠPÍREK Mário LOBIE Tekle Airgecho SKARSTAD Kirsten KREJČÍ Lumír BJORAS Magnar

  Article in Periodical

  Scientific reports, year: 2020, volume: 10, edition: 1, DOI

• DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs

  ŠTEFANOVIE Barbora HENGEL Sarah R. MLČOUŠKOVÁ Jarmila PROCHAZKOVA Jana ŠPÍREK Mário NIKULENKOV Fedor NĚMEČEK Daniel KOCH Brandon G. BAIN Fletcher E. YU Liping SPIES Maria KREJČÍ Lumír

  Article in Periodical

  Nucleic Acids Research, year: 2020, volume: 48, edition: 2, DOI

• RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops

  FERETZAKI Marianna POSPÍŠILOVÁ Michaela VALADOR FERNANDES Rita LUNARDI Thomas KREJČÍ Lumír LINGNER Joachim

  Article in Periodical

  Nature, year: 2020, volume: 587, edition: 7833, DOI

• SAMHD1 acts at stalled replication forks to prevent interferon induction

  COQUEL Flavie SILVA Maria-Joao TECHER Hervé ZADOROZHNY Karina SHARMA Sushma NIEMINUSZCZY Jadwiga METTLING Clément DARDILLAC Elodie BARTHE Antoine SCHMITZ Anne-Lyne PROMONET Alexy CRIBIER Alexandra SARRAZIN Amélie NIEDZWIEDZ Wojciech LOPEZ Bernard COSTANZO Vincenzo KREJČÍ Lumír CHABES Andrei BENKIRANE Monsef YEA-LIH Lin PASERO Philippe

  Article in Periodical

  Comptes Rendus - Biologies, year: 2020, volume: 343, edition: 1, DOI

• The CHK1 inhibitor MU380 significantly increases the sensitivity of human docetaxel-resistant prostate cancer cells to gemcitabine through the induction of mitotic catastrophe

  DRÁPELA Stanislav KHIRSARIYA PrashantKumar VAN WEERDEN Wytske M FEDR Radek SUCHÁNKOVÁ Tereza BÍZOVA Diana ČERVENÝ Jan HAMPL Aleš PUHR Martin WATSON William R CULIG Zoran KREJČÍ Lumír PARUCH Kamil SOUČEK Karel

  Article in Periodical

  Molecular oncology, year: 2020, volume: 14, edition: 10, DOI

• TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51(K133A)

  KO Jun Ho SON Mi Young ZHOU Qing MOLNÁROVÁ Lucia SONG Lambert MLCOUSKOVA Jarmila JEKABSONS Atis MONTAGNA Cristina KREJČÍ Lumír HASTY Paul

  Article in Periodical

  Cell Reports, year: 2020, volume: 33, edition: 12, DOI

2019

• CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes

  CHIRACKAL MANAVALAN Anil Paul PILAŘOVÁ Květa KLUGE Michael BARTHOLOMEEUSEN Koen RÁJECKÝ Michal OPPELT Jan KHIRSARIYA PrashantKumar PARUCH Kamil KREJČÍ Lumír FRIEDEL Caroline C BLAŽEK Dalibor

  Article in Periodical

  EMBO reports, year: 2019, volume: 20, edition: 9, DOI

• Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome

  BERESHCHENKO Oxana LO RE Oriana NIKULENKOV Fedor FLAMINI Sara KOTAŠKOVÁ Jana MAZZA Tommaso LE PANNERER Marguerite-Mari BUSCHBECK Marcus GIALLONGO Cesarina PALUMBO Giuseppe LI VOLTI Giovanni PAZIENZA Valerio ČERVINEK Libor RICCARDI Carlo KREJČÍ Lumír POSPÍŠILOVÁ Šárka STEWART A. Francis VINCIGUERRA Manlio

  Article in Periodical

  CLINICAL EPIGENETICS, year: 2019, volume: 11, edition: 1, DOI