2017

• Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments

  KOLINJIVADI A.M. SANNINO V. DE ANTONI A. MOVSESJAN Karina KILKENNY M. TECHER H. BALDI G. SHEN R. CICCIA A. PELLEGRINI L. KREJČÍ Lumír COSTANZO V.

  Article in Periodical

  Molecular Cell, year: 2017, volume: 67, edition: 5, DOI

• Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation

  SAMADDER Pounami SUCHÁNKOVÁ Tereza HYLSE Ondřej KHIRSARIYA PrashantKumar NIKULENKOV Fedor DRÁPELA Stanislav STRAKOVÁ Nicol VAŇHARA Petr VAŠÍČKOVÁ Kateřina KOLÁŘOVÁ Hana BINÓ Lucia BITTOVÁ Miroslava OVESNÁ Petra KOLLÁR Peter FEDR Radek EŠNER Milan JAROŠ Josef HAMPL Aleš KREJČÍ Lumír PARUCH Kamil SOUČEK Karel

  Article in Periodical

  Molecular Cancer Therapeutics, year: 2017, volume: 16, edition: 9, DOI

• Unloading of homologous recombination factors is required for restoring double-stranded DNA at damage repair loci

  VASIANOVICH Yulia ALTMANNOVÁ Veronika KOTENKO Oleksii NEWTON Matthew D. KREJČÍ Lumír MAKOVETS Svetlana

  Article in Periodical

  EMBO Journal, year: 2017, volume: 36, edition: 2, DOI

2016

• A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling

  TAYLOR Martin R.G. ŠPÍREK Mário MA Chu Jian CARZANIGA Raffaella TAKAKI Tohru COLLINSON Lucy M. GREENE Eric C. KREJČÍ Lumír BOULTON Simon J.

  Article in Periodical

  Molecular Cell, year: 2016, volume: 64, edition: 5, DOI

• Cancer TARGETases: DSB Repair as a Pharmacological Target

  SAMADDER Pounami AITHAL Rakesh BELÁŇ Ondrej KREJČÍ Lumír

  Article in Periodical

  Pharmacology & Therapeutics, year: 2016, volume: 161, edition: "May", DOI

• DNA, the central molecule of aging

  LÉNÁRT Peter KREJČÍ Lumír

  Article in Periodical

  Mutation Research / Fundamental and Molecular Mechanisms of Mutagenesis, year: 2016, volume: 786, edition: "April", DOI

• Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission

  SHYAMSUNDER Pavithra EŠNER Milan BARVALIA Maunish WU Yu Jun LOJA Tomáš BOON Huat Bay LLEONART Matilde E. VERMA Rama S KREJČÍ Lumír LYAKHOVICH Alex

  Article in Periodical

  Oncotarget, year: 2016, volume: 7, edition: 36, DOI

• Mitochondrial dysfunction in DDR-related cancer predisposition syndromes

  LYAKHOVICH Alex GRAIFER Dmitry ŠTEFANOVIE Barbora KREJČÍ Lumír

  Article in Periodical

  Biochimica et Biophysica Acta - Reviews on Cancer, year: 2016, volume: 1865, edition: 2, DOI

• Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance

  SILVA Sonia ALTMANNOVÁ Veronika LUKE-GLASER Sarah HENRIKSEN Peter GALLINA Irene YANG Xuejiao CHOUDHARY Chunaram LUKE Brian KREJČÍ Lumír LISBY Michael

  Article in Periodical

  Genes & Development, year: 2016, volume: 30, edition: 6, DOI

• Pro-recombination Role of Srs2 Protein Requires SUMO (Small ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction

  KOLESÁR Peter ALTMANNOVÁ Veronika SILVA Sonia LISBY Michael KREJČÍ Lumír

  Article in Periodical

  Journal of Biological Chemistry, year: 2016, volume: 291, edition: 14, DOI